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Chemokine (C-X-C Motif) Receptor 4 (CXCR4) Peptide

CXCR4 适用: 人 宿主: 合成 BP, WB, IHC, FACS
产品编号 ABIN975479
发货至: 中国
  • 抗原 See all CXCR4 products
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    宿主
    资源
    • 6
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-CXCR4 antibody (Catalog #: ARP30799_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    别名
    CD184 Peptide, D2S201E Peptide, FB22 Peptide, HM89 Peptide, HSY3RR Peptide, LAP3 Peptide, LCR1 Peptide, LESTR Peptide, NPY3R Peptide, NPYR Peptide, NPYRL Peptide, NPYY3R Peptide, WHIM Peptide, Cmkar4 Peptide, PB-CKR Peptide, PBSF/SDF-1 Peptide, Sdf1r Peptide, CXC-R4-B Peptide, CXCR-4-B Peptide, cd184 Peptide, cxcr4 Peptide, fb22 Peptide, hm89 Peptide, hsy3rr Peptide, lap3 Peptide, lcr1 Peptide, lestr Peptide, npy3r Peptide, npyr Peptide, npyrl Peptide, npyy3r Peptide, xcxcr4 Peptide, CXC-R4 Peptide, CXCR-4 Peptide, d2s201e Peptide, whim Peptide, CXC-R4-A Peptide, CXCR-4-A Peptide, xCXCR4 Peptide, CXCR4 Peptide, cb403 Peptide, zgc:109863 Peptide, cb824 Peptide, C-X-C motif chemokine receptor 4 Peptide, chemokine (C-X-C motif) receptor 4 Peptide, C-X-C motif chemokine receptor 4 S homeolog Peptide, C-X-C chemokine receptor type 4 Peptide, C-X-C motif chemokine receptor 4 L homeolog Peptide, chemokine (C-X-C motif), receptor 4b Peptide, chemokine (C-X-C motif) receptor 4a Peptide, CXCR4 Peptide, Cxcr4 Peptide, cxcr4.S Peptide, cxcr4 Peptide, LOC100049444 Peptide, cxcr4.L Peptide, cxcr4b Peptide, cxcr4a Peptide
    背景
    CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Alias Symbols: CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM

    Protein Interaction Partner: CXCL12,ADRBK2,ARRB2,CCR5,CD4,CTSG,CXCL12,CXCR4,DPP4,ELANE,GNA13,GNAI1,HSPA8,JAK1,JAK2,JAK3,MYH9,PTK2,PTPN11,PTPN6,PTPRC,SDC4,SOCS1,SOCS3,STAT1,STAT2,STAT3,STAT5B,VAV1,ADRBK2,CCR5,CD4,ITCH,JAK2,JAK3,PTK2,PTPN6,SOCS3,UBC,USP14

    Protein Size: 352
    分子量
    40 kDa
    基因ID
    7852
    NCBI登录号
    NM_003467, NP_003458
    UniProt
    P61073
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