Chemokine (C-X-C Motif) Receptor 4 (CXCR4) Peptide
CXCR4
适用: 人
宿主: 合成
BP, WB, IHC, FACS
产品编号 ABIN975479
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Chemokine (C-X-C Motif) Receptor 4 (CXCR4) Peptide (ABIN975479)
抗原
CXCR4
(Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CXCR4 antibody (Catalog #: ARP30799_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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Chemokine (C-X-C Motif) Receptor 4 (CXCR4) peptide
CXCR4 宿主: 合成 BP, WB, IHC
Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 26-37) peptide (Ovalbumin)CXCR4 适用: 人 宿主: 合成 WB, Imm, SDS
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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背景
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CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
Protein Interaction Partner: CXCL12,ADRBK2,ARRB2,CCR5,CD4,CTSG,CXCL12,CXCR4,DPP4,ELANE,GNA13,GNAI1,HSPA8,JAK1,JAK2,JAK3,MYH9,PTK2,PTPN11,PTPN6,PTPRC,SDC4,SOCS1,SOCS3,STAT1,STAT2,STAT3,STAT5B,VAV1,ADRBK2,CCR5,CD4,ITCH,JAK2,JAK3,PTK2,PTPN6,SOCS3,UBC,USP14
Protein Size: 352 -
分子量
- 40 kDa
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基因ID
- 7852
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NCBI登录号
- NM_003467, NP_003458
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UniProt
- P61073
抗原
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