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Cathepsin K (CTSK) (Middle Region) Peptide

CTSK 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN975444
发货至: 中国
  • 抗原 See all Cathepsin K (CTSK) products
    Cathepsin K (CTSK)
    蛋白结构域
    Middle Region
    宿主
    资源
    • 4
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    SPQNLVDCVS ENDGCGGGYM TNAFQYVQKN RGIDSEDAYP YVGQEESCMY
    产品特性
    This is a synthetic peptide designed for use in combination with anti-CTSK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    Cathepsin K (CTSK)
    背景
    The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.

    Alias Symbols: CTS02, CTSO, CTSO1, CTSO2, MGC23107, PKND, PYCD

    Protein Interaction Partner: FGFR3,KNG1,SERPINB13,SERPINB3,SPARC,FGFR3,SERPINB3

    Protein Size: 329
    分子量
    37 kDa
    基因ID
    1513
    NCBI登录号
    NM_000396, NP_000387
    UniProt
    P43235
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