Casein Kinase 1, epsilon (CSNK1E) (N-Term) Peptide
CSNK1E
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN975370
发货至:
中国
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Quick Overview for Casein Kinase 1, epsilon (CSNK1E) (N-Term) Peptide (ABIN975370)
抗原
CK1 epsilon (CSNK1E)
(Casein Kinase 1, epsilon (CSNK1E))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CSNK1E antibody (Catalog #: ARP51987_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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Casein Kinase 1, epsilon (CSNK1E) peptide
CSNK1E 适用: 人, 小鼠, 大鼠, 犬 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))
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背景
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Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CSNK1E can phosphorylate a large number of proteins. CSNK1E participates in Wnt signaling and is the central component of the circadian clock. It may act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. CSNK1E inhibits cytokine-induced granuloytic differentiation.The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: HCKIE, MGC10398, CKIepsilon
Protein Interaction Partner: ESR1,AKAP9,ANKRD6,APC,ARNTL,AXIN1,AXIN2,BID,CRY1,CSNK1E,DVL1,DVL2,DVL3,OCLN,PER1,PER2,PER3,PPP1R14A,RAD54B,SOCS3,ANKRD6,ARNTL,AXIN1,Cry1,DVL1,DVL2,MCC,PER1,PER3,RAD54B,Trp53
Protein Size: 416 -
分子量
- 47 kDa
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基因ID
- 1454
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NCBI登录号
- NM_001894, NP_001885
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UniProt
- P49674
抗原
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