Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) Peptide
KCNIP3
适用: 人
宿主: 合成
BP, WB, IHC
产品编号 ABIN975353
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) Peptide (ABIN975353)
抗原
DREAM (KCNIP3)
(Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CSEN antibody (Catalog #: ARP31932_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
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背景
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CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.
Alias Symbols: CSEN, DREAM, KCHIP3
Protein Interaction Partner: CASP3,CD177,CREB1,CREM,PSEN1,PSEN2,CD177,CREB1,CREM,CRK,PSEN1,PSEN2
Protein Size: 256 -
分子量
- 29 kDa
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基因ID
- 30818
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NCBI登录号
- NM_013434, NP_038462
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UniProt
- Q9Y2W7
抗原
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