V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (Middle Region) Peptide
CRKL
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all CrkL (CRKL) products
- CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- RSSPHGKHGN RNSNSYGIPE PAHAYAQPQT TTPLPAVSGS PGAAITPLPS
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-CRKL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) peptide
CRKL 适用: 人, 小鼠, 大鼠 宿主: 合成 BP, Imm
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
- 别名
- CRKL Peptide, wu:fa55g05 Peptide, wu:fj60e01 Peptide, zgc:63469 Peptide, 1110025F07Rik Peptide, AA589403 Peptide, AI325100 Peptide, Crkol Peptide, CRK like proto-oncogene, adaptor protein Peptide, v-crk avian sarcoma virus CT10 oncogene homolog-like Peptide, CRKL Peptide, crkl Peptide, Crkl Peptide
- 背景
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CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential.
Alias Symbols: -
Protein Size: 303 - 分子量
- 34 kDa
- 基因ID
- 1399
- NCBI登录号
- NM_005207, NP_005198
- UniProt
- P46109
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