V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (Middle Region) Peptide
CRKL
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN975318
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (Middle Region) Peptide (ABIN975318)
抗原
CrkL (CRKL)
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- RSSPHGKHGN RNSNSYGIPE PAHAYAQPQT TTPLPAVSGS PGAAITPLPS
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CRKL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) peptide
CRKL 适用: 人, 小鼠, 大鼠 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
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背景
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CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential.
Alias Symbols: -
Protein Size: 303 -
分子量
- 34 kDa
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基因ID
- 1399
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NCBI登录号
- NM_005207, NP_005198
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UniProt
- P46109
抗原
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