Cortistatin (CORT) (N-Term) Peptide
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Quick Overview for Cortistatin (CORT) (N-Term) Peptide (ABIN975212)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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序列
- MPLSPGLLLL LLSGATATAA LPLEGGPTGR DSEHMQEAAG IRKSSLLTFL
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CORT Antibody(ARP59541_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CORT (Cortistatin (CORT))
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背景
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This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739.
Alias Symbols: CST-14, CST-17, CST-29
Protein Interaction Partner: GHSR,MRGPRX2,SSTR1,SSTR2,SSTR3,SSTR4,SSTR5,SSTR1,SSTR2,SSTR3,SSTR4,SSTR5
Protein Size: 155 -
分子量
- 2 kDa
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基因ID
- 1325
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NCBI登录号
- NM_001302, NP_001293
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UniProt
- O00230
抗原
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