Chymase 1, Mast Cell (CMA1) (C-Term) Peptide
CMA1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all CMA1 products
- CMA1 (Chymase 1, Mast Cell (CMA1))
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- EVKLRLMDPQ ACSHFRDFDH NLQLCVGNPR KTKSAFKGDS GGPLLCAGVA
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-CMA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- CMA1 (Chymase 1, Mast Cell (CMA1))
- 背景
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CMA1 is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies.
Alias Symbols: CYH, MCT1, MGC119890, MGC119891, chymase
Protein Interaction Partner: AGT,EDN1,EDN2,EDN3,KITLG,MMP1,PFN1,SERPINA3
Protein Size: 247 - 分子量
- 27 kDa
- 基因ID
- 1215
- NCBI登录号
- NM_001836, NP_001827
- UniProt
- P23946
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