Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (C-Term) Peptide
CILP
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN974989
发货至:
中国
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Contact Info
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中国
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Quick Overview for Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (C-Term) Peptide (ABIN974989)
抗原
CILP
(Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- YIKVKIVGPL EVNVRSRNMG GTHRQTVGKL YGIRDVRSTR DRDQPNVSAA
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CILP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) peptide
CILP 适用: 人, 大鼠, 犬, 小鼠 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
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背景
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Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins, an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.
Alias Symbols: CILP-1, HsT18872
Protein Size: 1184 -
分子量
- 52 kDa
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基因ID
- 8483
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NCBI登录号
- NM_003613, NP_003604
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UniProt
- O75339
抗原
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