Charged Multivesicular Body Protein 4B (CHMP4B) (Middle Region) Peptide
CHMP4B
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN974931
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for Charged Multivesicular Body Protein 4B (CHMP4B) (Middle Region) Peptide (ABIN974931)
抗原
CHMP4B
(Charged Multivesicular Body Protein 4B (CHMP4B))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- EEISTAISKP VGFGEEFDED ELMAELEELE QEELDKNLLE ISGPETVPLP
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CHMP4B Antibody(ARP53340_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
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背景
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This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.
Alias Symbols: C20orf178, CHMP4A, CTPP3, SNF7, SNF7-2, Shax1, dJ553F4.4, VPS32B, Vps32-2
Protein Interaction Partner: PDCD6IP,CHMP1B,CHMP4A,CHMP4B,CHMP4C,CHMP5,CHMP6,EXOSC9,HIPK2,PDCD6IP,PIAS2,STAMBP,UBE2I,VPS24,VPS4A,UBE2I
Protein Size: 224 -
分子量
- 25 kDa
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基因ID
- 128866
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NCBI登录号
- NM_176812, NP_789782
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UniProt
- Q9H444
抗原
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