CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (N-Term) Peptide
CEBPB
适用: 人
宿主: 合成
BP, WB
Quick Overview for CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (N-Term) Peptide (ABIN974820)
抗原
CEBPB
(CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CEBPB antibody (Catalog #: ARP57940_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))
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背景
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CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: C/EBP-beta, CRP2, IL6DBP, LAP, MGC32080, NF-IL6, TCF5
Protein Interaction Partner: DDIT3,EGR1,PRG2,SMAD4,ATF2,ATF4,CAMK2A,CCL3,CEBPA,CEBPB,CEBPD,CEBPG,CREB1,CREBBP,DDIT3,EGFR,EGR1,ELK1,EP300,ESR1,FOXO1,HMGA1,HMGB1,HNRNPK,HOMER3,HSF1,MAPK1,MAPK3,MED23,MYB,MYC,NFKB1,NOLC1,NR3C1,PTGES2,RB1,RELA,RPS6KA1,RPS6KA5,RUNX1,RUNX2,SMAD3,SMAD4,SMARCA4,SMARCB1,SMARCC1,SP1,SPI1,SPIB,SRF,STAT5A,STAT6,TAF9,TRIM28,AR,Atf2,CDK8,CEBPA,CEBPD,CEBPG,CREB1,DDIT3,EGFR,EGR1,EP300,ESR1,FOXO1,HMGA1,HNRNPK,HSF1,MAPK1,MED23,MED26,MYB,MYC,NFKB1,NOLC1,NR3C1,RARB,RB1,RELA,RUNX1,SMAD3,SMAD4,SMARCA2,SMARCC1,SP1,SPI1,SRF,TRIM28
Protein Size: 345 -
分子量
- 36 kDa
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基因ID
- 1051
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NCBI登录号
- NM_005194, NP_005185
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UniProt
- P17676
抗原
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