P-Cadherin (CDH3) Peptide
CDH3
适用: 人
宿主: 合成
BP, IHC, WB
Quick Overview for P-Cadherin (CDH3) Peptide (ABIN974754)
抗原
P-Cadherin (CDH3)
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CDH3 antibody (Catalog #: ARP45170_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- P-Cadherin (CDH3)
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背景
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CDH3 is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Its gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in its gene have been associated with congential hypotrichosis with juvenile macular dystrophy.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
Alias Symbols: CDHP, HJMD, PCAD
Protein Interaction Partner: CDH3,CTNNA1,CTNNB1,CTNND1,CD2AP,CDH1,CDH3,CTNNA1,CTNNB1,CTNND1,JUP,NPHS1
Protein Size: 829 -
分子量
- 91 kDa
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基因ID
- 1001
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NCBI登录号
- NM_001793, NP_001784
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UniProt
- P22223
抗原
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