Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27) (Middle Region) Peptide
CDC27
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN974728
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27) (Middle Region) Peptide (ABIN974728)
抗原
CDC27
(Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- KLKMKFPPKI PNRKTKSKTN KGGITQPNIN DSLEITKLDS SIISEGKIST
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CDC27 Antibody(ARP43603_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CDC27 (Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27))
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背景
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The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, NUC2, ANAPC3
Protein Interaction Partner: FZR1,PIN1,ANAPC10,ANAPC2,ANAPC7,BUB1B,CASP3,CDC16,CDC20,CDC26,FZR1,HOXC10,MAD2L1,PIN1,PPP5C,RB1,SKIL,SMAD2,SMAD3,ANAPC1,ANAPC10,ANAPC11,ANAPC2,ANAPC4,ANAPC5,ANAPC7,APC2,BUB1B,CCNB1,CDC16,CDC20,CDC23,CDC26,CDH1,CDKN1A,CTNNB1,FZR1,MAD2L1,PIN1,PPP5C,PTTG1,Pp
Protein Size: 824 -
分子量
- 92 kDa
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基因ID
- 996
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NCBI登录号
- NM_001256, NP_001247
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UniProt
- P30260
抗原
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