Cyclin-Dependent Kinase 1 (CDK1) (N-Term) Peptide
CDK1
适用: 人
宿主: 合成
BP, WB
Quick Overview for Cyclin-Dependent Kinase 1 (CDK1) (N-Term) Peptide (ABIN974713)
抗原
CDK1
(Cyclin-Dependent Kinase 1 (CDK1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CDC2 antibody (Catalog #: AVARP01020_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
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背景
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The protein encoded by CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Alias Symbols: CDC28A, CDK1, DKFZp686L20222, MGC111195, CDC2, P34CDC2
Protein Interaction Partner: E2F1,E2F3,E2F4,E2F4,E2F4,NRF1,CCNA1,CCNA2,CCNB1,CCNB1,CCNB1,CCNB2,CCNB2,CDKN1A,MDM4,PITPNM1,PKMYT1,WEE1,ABL1,AMPH,APLP2,AR,BIRC5,BRCA1,BRCA2,BUB1,C13orf15,CALD1,CCNA1,CCNA2,CCNB1,CCNB2,CCNE1,CDC25A,CDC25B,CDC25C,CDK1,CDK7,CDKN1A,CDKN3,CDT1,CEP55,CHAF1B,CKS2,CNOT7,CREM,CSNK2A1,CSNK2B,CUX1,DAB2,DNM2,DUT,E2F1,ECT2,EEF1D,EPN1,ERCC2,FANCA,FANCC,FANCG,FEN1,FOXM1,FYN,GADD45A,GADD45B,GADD45G,GFAP,GOLGA2,GORASP1,HMGA1,HMGA2,HSPA2,IL16,ITPR1,KAT5,KHDRBS1,KIF11,KIF20B,KRT18,LATS1,LMNA,LMNB1,LYN,LZTS1,MAP4,MAPT,MCM4,MDM4,MEF2C,MNDA,MYC,MYT1,NDE1,NES,NPM1,NSFL1C,NUP210,PBK,PCNA,PIN1,PITPNM1,PKMYT1,PLEC,POLA1,PPP2R1A,PPP2R1B,PTCH1,PTMA,PTPN1,PTPN2,PTTG1,RAB4A,RAB5B,RAP1GAP,RB1,RCC1,RPA2,RPS6KB1,RRM2,RUNX2,SFN,SPAG5,STMN1,STMN2,TGFBR2,TK1,TLE1,TOP2A,TP53,TP73,TSC1,UBA1,UBE2A,USP16,VIM,WEE1,ZBTB16,BCL2,BRCA1,CCNA1,CCNA2,CCNA2,CCNB1,CCNB1,CCNB1,CCNB1,CCNE1,CCNF,CDC25C,CDKN1A,CDKN3,CIITA,CNOT7,CUX1,DAB2,ESPL1,FANCA,FANCC,FANCG,FEN1,FYN,GADD45A,GADD45A,GADD45B,GADD45B,GADD45G,GADD45G,HIST1H1A,HMGB1,HSPA4,LATS1,LYN,LZTS1,MAP4,MKI67,NSFL1C,PRKCB,SFN,SPAG5,TP53,TSC1,UBC,UIMC1,USP19,USP32,USP45,ZBTB16
Protein Size: 297 -
分子量
- 34 kDa
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基因ID
- 983
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NCBI登录号
- NM_001786, NP_001777
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UniProt
- P06493
抗原
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