This is a synthetic peptide designed for use in combination with anti-CBX1 antibody (Catalog #: ARP34427_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
CBX1
(Chromobox Homolog 1 (CBX1))
背景
CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.Heterochromatin protein-1 (HP1) is localized at heterochromatin sites, where it mediates gene silencing.[supplied by OMIM].
Alias Symbols: CBX, M31, MOD1, p25beta, HP1-BETA, HP1Hsbeta, HP1Hs-beta
Protein Interaction Partner: DNMT3B,MKI67,ARL5A,C11orf30,C1orf103,CBX1,CBX3,CBX5,CHAF1A,DNMT1,DNMT3A,DNMT3B,HIST1H1E,HIST1H3A,HIST1H3C,HIST3H3,PIM1,RPL12,SUV39H1,TRIM24,TRIM28,UCHL1,ARL5A,BAP1,C11orf30,C1orf103,CBX1,CBX3,CBX5,DNMT1,DNMT3A,MYOD1,PIM1,RB1,RPL12,SP100,SUV39H1,Suv39h1,TRIM28,UCHL1,USP17L2