Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (N-Term) Peptide
CASP7
适用: 人
宿主: 合成
BP, WB
Quick Overview for Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (N-Term) Peptide (ABIN974478)
抗原
Caspase 7 (CASP7)
(Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- NNKNFDKVTG MGVRNGTDKD AEALFKCFRS LGFDVIVYND CSCAKMQDLL
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CASP7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
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背景
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This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.
Alias Symbols: CMH-1, ICE-LAP3, MCH3
Protein Interaction Partner: AR,ATN1,BIRC3,CTSG,GZMB,HTT,PARP1,PSEN1,RB1,XIAP,AR,BIRC2,BIRC3,BIRC5,BIRC7,CASP10,CASP2,CASP7,CAST,CDC42,CFLAR,CLSPN,CTSG,DCTN1,DFFA,DSP,EIF2AK2,GOLGA3,GORASP1,GZMB,HSPA5,KRT18,LYN,MAPT,MAX,MEF2A,MEF2D,NEDD4,PRKCZ,PSEN1,PSEN2,PSIP1,PSME3,PTMA,RAC1,RAD21,
Protein Size: 336 -
分子量
- 37 kDa
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基因ID
- 840
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NCBI登录号
- NM_033338, NP_203124
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UniProt
- P55210
抗原
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