Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (Middle Region) Peptide
CASP5
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN974476
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (Middle Region) Peptide (ABIN974476)
抗原
CASP5
(Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- VIIVQACRGE KHGELWVRDS PASLALISSQ SSENLEADSV CKIHEEKDFI
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CASP5 Antibody(ARP58992_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
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背景
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This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
Alias Symbols: ICE(rel)III, ICEREL-III, ICH-3, MGC141966
Protein Interaction Partner: CASP5,MAX,NLRP1,PPHLN1,PPHLN1
Protein Size: 376 -
分子量
- 43 kDa
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基因ID
- 838
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NCBI登录号
- NM_001136109, NP_001129581
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UniProt
- P51878
抗原
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