Caspase 3 (CASP3) (C-Term) Peptide
CASP3
适用: 人
宿主: 合成
BP, WB, IHC
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- 抗原 See all Caspase 3 (CASP3) products
- Caspase 3 (CASP3)
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- NLKYEVRNKN DLTREEIVEL MRDVSKEDHS KRSSFVCVLL SHGEEGIIFG
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-CASP3 Antibody(ARP58987_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- Caspase 3 (CASP3)
- 背景
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CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Alias Symbols: CPP32, CPP32B, SCA-1
Protein Interaction Partner: AR,ATN1,ATXN3,BIRC3,BIRC6,HTT,NDUFS1,NEO1,PARP1,PLEKHO1,XIAP,BIRC6,CFLAR,PSEN1,RB1,XIAP,ACIN1,ADD1,AIFM1,AKAP8,AKT1,APAF1,APP,AR,ARHGDIB,ATN1,BCAP31,BCAR1,BCL2,BID,BIRC2,BIRC3,BIRC5,BIRC6,BIRC7,BLM,BMX,BRCA1,CAD,CASP10,CASP3,CASP4,CASP6,CASP8,CASP9,CAST,C
Protein Size: 277 - 分子量
- 12 kDa
- 基因ID
- 836
- NCBI登录号
- NM_032991, NP_116786
- UniProt
- P42574
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