Caspase Recruitment Domain Family, Member 17 (CARD17) (Middle Region) Peptide
CARD17
适用: 人
宿主: 合成
BP, WB
Quick Overview for Caspase Recruitment Domain Family, Member 17 (CARD17) (Middle Region) Peptide (ABIN974462)
抗原
CARD17
(Caspase Recruitment Domain Family, Member 17 (CARD17))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- MDKARALLDS VIRKGAPACQ ICITYICEED SHLAGTLGLS AGPTSGNHLT
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CARD17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CARD17 (Caspase Recruitment Domain Family, Member 17 (CARD17))
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背景
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As a regulator of procaspase-1/CASP1 activation, CARD17 is implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. CARD17 inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, CARD17 do not induce NF-kappa-B activation.
Alias Symbols: INCA
Protein Interaction Partner: CARD16,CARD17,CARD18,CASP1
Protein Size: 110 -
分子量
- 12 kDa
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基因ID
- 440068
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NCBI登录号
- NM_001007232, NP_001007233
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UniProt
- Q5XLA6
抗原
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