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Bol, Boule-Like (BOLL) Peptide

BOLL 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN973860
发货至: 中国

Quick Overview for Bol, Boule-Like (BOLL) Peptide (ABIN973860)

抗原

BOLL (Bol, Boule-Like (BOLL))

宿主

资源

  • 3
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 产品特性

    This is a synthetic peptide designed for use in combination with anti-BOLL antibody (Catalog #: ARP41065_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    BOLL (Bol, Boule-Like (BOLL))

    背景

    This gene belongs to the DAZ gene family required for germ cell development. BOLL is an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    Alias Symbols: BOULE

    Protein Interaction Partner: DAZ1,DAZ4

    Protein Size: 283

    分子量

    31 kDa

    基因ID

    66037

    NCBI登录号

    NM_033030, NP_149019

    UniProt

    Q8N9W6
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