BMI1 Polycomb Ring Finger Oncogene (BMI1) (Middle Region) Peptide
BMI1
适用: 人, 小鼠
宿主: 合成
BP, WB
Quick Overview for BMI1 Polycomb Ring Finger Oncogene (BMI1) (Middle Region) Peptide (ABIN973837)
抗原
BMI1
(BMI1 Polycomb Ring Finger Oncogene (BMI1))
宿主
人, 小鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- MDIPNTFQID VMYEEEPLKD YYTLMDIAYI YTWRRNGPLP LKYRVRPTCK
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产品特性
- This is a synthetic peptide designed for use in combination with anti-Bmi1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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背景
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Bmi1 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Alias Symbols: AW546694, Bmi-1, Pcgf4
Protein Interaction Partner: Phc2,Rnf2,CBX4,CBX8,Cbx2,Dmap1,Dnmt3b,HSPA4,Kdm2b,PHC1,PHC2,PHC3,Phc1,Phc3,RING1,Rnf2,SCMH1,SMARCA5,Slc11a1
Protein Size: 324 -
分子量
- 37 kDa
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基因ID
- 12151
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NCBI登录号
- NM_007552, NP_031578
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UniProt
- P25916
抗原
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