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BH3 Interacting Domain Death Agonist (BID) (C-Term) Peptide

BID 适用: 人 宿主: 合成 BP, ICC, WB
产品编号 ABIN973819
发货至: 中国
  • 抗原 See all BID products
    BID (BH3 Interacting Domain Death Agonist (BID))
    蛋白结构域
    C-Term
    宿主
    资源
    • 5
    合成
    应用范围
    Blocking Peptide (BP), Immunocytochemistry (ICC), Western Blotting (WB)
    序列
    LRNTSRSEED RNRDLATALE QLLQAYPRDM EKEKTMLVLA LLLAKKVASH
    产品特性
    This is a synthetic peptide designed for use in combination with anti-BID Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    BID (BH3 Interacting Domain Death Agonist (BID))
    别名
    FP497 Peptide, 2700049M22Rik Peptide, AI875481 Peptide, AU022477 Peptide, BID Peptide, bid Peptide, si:ch211-238n5.6 Peptide, fp497 Peptide, xbid Peptide, DKFZp469E066 Peptide, BH3 interacting domain death agonist Peptide, BH3 interacting domain death agonist S homeolog Peptide, BID Peptide, Bid Peptide, bida Peptide, bid.S Peptide, bid Peptide
    背景
    This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

    Alias Symbols: FP497, MGC15319, MGC42355

    Protein Interaction Partner: BAX,BCL2,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L1,BCL2L2,BNC1,PACS2,BCL2L1,BAK1,BAX,BCL2,BCL2A1,BCL2L1,BCL2L2,BID,CAPN1,CASP1,CASP10,CASP2,CASP3,CASP8,CSNK1A1,CSNK1E,CSNK2A1,CSNK2A2,CSNK2B,GZMB,MCL1,YWHAB,ARHGDIA,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L2,BID,CAPN2,CASP10,

    Protein Size: 241
    分子量
    27 kDa
    基因ID
    637
    NCBI登录号
    NM_197966, NP_932070
    UniProt
    B3KT21
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