B-Cell CLL/lymphoma 2 (BCL2) (Middle Region) Peptide
BCL2
适用: 人
宿主: 合成
BP, WB
Quick Overview for B-Cell CLL/lymphoma 2 (BCL2) (Middle Region) Peptide (ABIN973780)
抗原
Bcl-2 (BCL2)
(B-Cell CLL/lymphoma 2 (BCL2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- ALSPVPPVVH LTLRQAGDDF SRRYRRDFAE MSSQLHLTPF TARGRFATVV
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产品特性
- This is a synthetic peptide designed for use in combination with anti-BCL2 Antibody(ARP58872_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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B-Cell CLL/lymphoma 2 (BCL2) peptide
BCL2 适用: 人, 小鼠, 大鼠, 犬 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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背景
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This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
Alias Symbols: Bcl-2, PPP1R50
Protein Interaction Partner: BAD,BAD,BAX,BBC3,BCL2L11,BID,BIK,BIK,BMF,BNIPL,HRK,HRK,RHEB,MOAP1,ATP2A2,BAD,BAG1,BAG3,BAG4,BAK1,BAX,BBC3,BCAP31,BCL2,BCL2L1,BCL2L10,BCL2L11,BCL2L14,BCLAF1,BECN1,BFAR,BID,BIK,BLK,BMF,BNIP1,BNIP2,BNIP3,BNIP3L,BNIPL,CASP3,CASP8,CDK2,CPT1A,CYCS,FKBP8,HRAS,HR
Protein Size: 239 -
分子量
- 26 kDa
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基因ID
- 596
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NCBI登录号
- NM_000633, NP_000624
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UniProt
- P10415
抗原
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