Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
产品特性
This is a synthetic peptide designed for use in combination with anti-BCL2 antibody (Catalog #: AVARP01005_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
Bcl-2 (BCL2)
(B-Cell CLL/lymphoma 2 (BCL2))
背景
The BCL2 gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.
Alias Symbols: Bcl-2, PPP1R50
Protein Interaction Partner: BAD,BAD,BAX,BBC3,BCL2L11,BID,BIK,BIK,BMF,BNIPL,HRK,HRK,RHEB,MOAP1,ATP2A2,BAD,BAG1,BAG3,BAG4,BAK1,BAX,BBC3,BCAP31,BCL2,BCL2L1,BCL2L10,BCL2L11,BCL2L14,BCLAF1,BECN1,BFAR,BID,BIK,BLK,BMF,BNIP1,BNIP2,BNIP3,BNIP3L,BNIPL,CASP3,CASP8,CDK2,CPT1A,CYCS,FKBP8,HRAS,HRK,HSPA1A,ITM2B,ITPR1,KRAS,MAPK1,MAPK11,MAPK14,MAPK3,MAPK8,MOAP1,MYC,NLRP1,NMT2,NR4A1,NRAS,PARP1,PIN1,PKMYT1,PMAIP1,PML,PPP1CA,PPP2CA,PPP2R5A,PPP3CA,PRKACA,PRKCA,PSEN1,PXN,RAD9A,RAF1,RRAS,RTN4,SF1,SMN2,SOD1,SPNS1,TMBIM6,TOMM20,TP53,TP53AIP1,TP53BP2,AVEN,BAD,BAD,BAG1,BAG3,BAG4,BAK1,BAX,BAX,BBC3,BBC3,BBC3,BBC3,BCAP31,BCL2L1,BCL2L10,BCL2L11,BECN1,BID,BID,BIK,BLK,BMF,BNIP1,BNIP2,BNIP3,BNIP3L,BNIPL,Bcl2l11,Becn1,CAPN2,CASP2,CASP3,CASP8,CDK1,DYNLL1,EPHB2,FKBP8,HRK,HSPA1A,IRS1,IRS2,ITM2B,ITPR1,MOAP1,MYC,NR4A1,PARP1,PIN1,PMAIP1,PPP2CA,PPP2R4,PPP2R5A,PPP3CA,PSEN1,RAD9A,RAF1,RRAS,RTN4,RTN4,SERPINB8,SMN1,SOD1,SPNS1,TMBIM6,TOMM20,TP53AIP1,TP53BP2,UBC