Bardet-Biedl Syndrome 4 (BBS4) (Middle Region) Peptide
BBS4
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN973753
发货至:
中国
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Contact Info
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中国
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Quick Overview for Bardet-Biedl Syndrome 4 (BBS4) (Middle Region) Peptide (ABIN973753)
抗原
BBS4
(Bardet-Biedl Syndrome 4 (BBS4))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- LGIYQKAFEH LGNALTYDPT NYKAILAAGS MMQTHGDFDV ALTKYRVVAC
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产品特性
- This is a synthetic peptide designed for use in combination with anti-BBS4 Antibody(ARP57696_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
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背景
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This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified.
Alias Symbols: -
Protein Interaction Partner: PCM1,DCTN1,PCM1
Protein Size: 519 -
分子量
- 58 kDa
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基因ID
- 585
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NCBI登录号
- NM_033028, NP_149017
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UniProt
- Q96RK4
抗原
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