BCL2-Associated X Protein (BAX) Peptide
BAX
适用: 人
宿主: 合成
BP, WB, IHC
Quick Overview for BCL2-Associated X Protein (BAX) Peptide (ABIN973743)
抗原
BAX
(BCL2-Associated X Protein (BAX))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-BAX antibody (Catalog #: AVARP02020_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
纯化方法
- Purified
-
-
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
浓度
- 1 mg/mL
-
缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- BAX (BCL2-Associated X Protein (BAX))
-
背景
-
BAX encodes a protein that belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. BAX expression is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.
Alias Symbols: BCL2L4
Protein Interaction Partner: TP53,TP53,TP73,BBC3,BCL2,BCL2,BCL2L1,BCL2L1,BID,MOAP1,NOL3,BAK1,BBC3,BCL2,BCL2A1,BCL2L1,BCL2L10,BID,ERN1,KCNA3,MCL1,MOAP1,NOL3,PMAIP1,PPP1CA,SFN,SH3GLB1,SLC25A4,VDAC1,YWHAQ,GTF2B,MUC1,TAF1,TBP,TP53,BAK1,BAX,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L10,BCL2L2,BNIPL,Bak1,CRYAA,CRYAB,HSPD1,MCL1,MEPCE,MOAP1,MOAP1,OYE2,PMAIP1,SH3GLB1,SH3GLB1,SLC25A4,SNCA,TOMM22,TOMM40,UBC,VDAC1,YWHAQ
Protein Size: 192 -
分子量
- 21 kDa
-
基因ID
- 581
-
NCBI登录号
- NM_138761, NP_620116
-
UniProt
- Q07812
抗原
-
You are here:
