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BCL2-Associated Athanogene 2 (BAG2) Peptide

BAG2 适用: 人 宿主: 合成 BP, IHC, WB
产品编号 ABIN973712
发货至: 中国
  • 抗原 See all BAG2 products
    BAG2 (BCL2-Associated Athanogene 2 (BAG2))
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-BAG2 antibody (Catalog #: ARP42177_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    BAG2 (BCL2-Associated Athanogene 2 (BAG2))
    别名
    bag2 Peptide, MGC89300 Peptide, BAG2 Peptide, ATBAG2 Peptide, BCL-2-associated athanogene 2 Peptide, MTG10.13 Peptide, MTG10_13 Peptide, BAG-2 Peptide, dJ417I1.2 Peptide, zgc:64195 Peptide, 2610042A13Rik Peptide, BC016230 Peptide, BCL2 associated athanogene 2 Peptide, BCL-2-associated athanogene 2 Peptide, BCL2-associated athanogene 2 Peptide, Bcl2-associated athanogene 2 Peptide, bag2 Peptide, BAG2 Peptide, Bag2 Peptide
    背景
    BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

    Alias Symbols: RP3-496N17.2, BAG-2, KIAA0576, MGC149462, dJ417I1.2

    Protein Interaction Partner: HSPA1A,HSPA8,MAPKAPK2,HSPA8,MLF2,PSMC4

    Protein Size: 211
    分子量
    23 kDa
    基因ID
    9532
    NCBI登录号
    NM_004282, NP_004273
    UniProt
    O95816
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