beta-Site APP-Cleaving Enzyme 2 (BACE2) (N-Term) Peptide
BACE2
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN973704
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for beta-Site APP-Cleaving Enzyme 2 (BACE2) (N-Term) Peptide (ABIN973704)
抗原
BACE2
(beta-Site APP-Cleaving Enzyme 2 (BACE2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
-
-
蛋白结构域
- N-Term
-
序列
- PAGAANFLAM VDNLQGDSGR GYYLEMLIGT PPQKLQILVD TGSSNFAVAG
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-BACE2 Antibody(ARP46853_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
纯化方法
- Purified
-
-
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
浓度
- 1 mg/mL
-
缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
-
背景
-
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: AEPLC, ALP56, ASP1, ASP21, BAE2, CDA13, CEAP1, DRAP
Protein Interaction Partner: APP,BACE2,GGA1,GGA2
Protein Size: 396 -
分子量
- 37 kDa
-
基因ID
- 25825
-
NCBI登录号
- NM_138992, NP_620477
-
UniProt
- Q9Y5Z0
抗原
-
You are here:
