beta-Site APP-Cleaving Enzyme 2 (BACE2) (Middle Region) Peptide
BACE2
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN973703
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for beta-Site APP-Cleaving Enzyme 2 (BACE2) (Middle Region) Peptide (ABIN973703)
抗原
BACE2
(beta-Site APP-Cleaving Enzyme 2 (BACE2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- SLNLDCREYN ADKAIVDSGT TLLRLPQKVF DAVVEAVARA SLIPEFSDGF
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产品特性
- This is a synthetic peptide designed for use in combination with anti-BACE2 Antibody(ARP46852_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
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背景
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Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: AEPLC, ALP56, ASP1, ASP21, BAE2, CDA13, CEAP1, DRAP
Protein Interaction Partner: APP,BACE2,GGA1,GGA2
Protein Size: 396 -
分子量
- 37 kDa
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基因ID
- 25825
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NCBI登录号
- NM_138992, NP_620477
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UniProt
- Q9Y5Z0
抗原
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