Artemin (ARTN) (Middle Region) Peptide
ARTN
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN973472
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Artemin (ARTN) (Middle Region) Peptide (ABIN973472)
抗原
ARTN
(Artemin (ARTN))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- RTARWCSGRA RRPPPQPSRP APPPPAPPSA LPRGGRAARA GGPGSRARAA
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产品特性
- This is a synthetic peptide designed for use in combination with anti-ARTN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ARTN (Artemin (ARTN))
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背景
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The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ENOVIN, EVN, NBN
Protein Interaction Partner: ARTN,GFRA3,GFRA3
Protein Size: 228 -
分子量
- 19 kDa
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基因ID
- 9048
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NCBI登录号
- NM_057090, NP_476431
抗原
-
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