Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (Middle Region) Peptide
APEX1
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN973301
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (Middle Region) Peptide (ABIN973301)
抗原
APEX1
(Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- HEEIDLRNPK GNKKNAGFTP QERQGFGELL QAVPLADSFR HLYPNTPYAY
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产品特性
- This is a synthetic peptide designed for use in combination with anti-APEX1 Antibody(ARP58028_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
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背景
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Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene, all encode the same protein.
Alias Symbols: APE, APE1, APEN, APEX, APX, HAP1, REF-1, REF1
Protein Interaction Partner: CDKN1A,MUTYH,TP53,ANP32A,ANP32C,APEX1,CSNK2A1,DCTN1,EP300,FEN1,GZMA,HDAC1,HIF1A,HMGB2,HNRNPL,HSPA1A,MUTYH,NME1,NXF2,PCNA,POLB,SET,TP53,TXN,UBE2I,XRCC1,XRCC6,ANP32A,FEN1,HIF1A,HNRNPL,MUTYH,PCNA,SET,TP53,XRCC1,XRCC5
Protein Size: 318 -
分子量
- 35 kDa
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基因ID
- 328
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NCBI登录号
- NM_001641, NP_001632
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UniProt
- P27695
抗原
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