Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A) Peptide
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Quick Overview for Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A) Peptide (ABIN973240)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-ANP32A antibody (Catalog #: ARP40203_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))
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背景
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ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity.
Alias Symbols: LANP, MAPM, PP32, HPPCn, PHAP1, PHAPI, I1PP2A, C15orf1
Protein Interaction Partner: ESR1,RARA,THRB,ADAP1,APEX1,ATXN1,AXIN1,E4F1,ELAVL1,HSPB3,KPNA1,KPNA5,KPNA6,MAP1B,NSFL1C,PTPRC,SET,ADAP1,APEX1,ATXN1,AXIN1,HIST3H3,HIST4H4,HSPB3,MAP1B,MEPCE,SET,TAF1A
Protein Size: 249 -
分子量
- 29 kDa
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基因ID
- 8125
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NCBI登录号
- NM_006305, NP_006296
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UniProt
- P39687
抗原
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