Angiopoietin 1 (ANGPT1) (N-Term) Peptide
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Quick Overview for Angiopoietin 1 (ANGPT1) (N-Term) Peptide (ABIN973195)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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序列
- FAFLAAILTH IGCSNQRRSP ENSGRRYNRI QHGQCAYTFI LPEHDGNCRE
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产品特性
- This is a synthetic peptide designed for use in combination with anti-ANGPT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Angiopoietin 1 (ANGPT1)
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背景
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Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: AGP1, AGPT, ANG1
Protein Interaction Partner: ANGPT1,ANGPT2,ITGA5,TEK,TEK,TEK
Protein Size: 498 -
分子量
- 55 kDa
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基因ID
- 284
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NCBI登录号
- NM_001146, NP_001137
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UniProt
- Q15389
抗原
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