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alpha-Methylacyl-CoA Racemase (AMACR) (C-Term) Peptide

AMACR 适用: 人 宿主: 合成 BP, WB, IHC
产品编号 ABIN973162
发货至: 中国

Quick Overview for alpha-Methylacyl-CoA Racemase (AMACR) (C-Term) Peptide (ABIN973162)

抗原

AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

宿主

资源

  • 8
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • 蛋白结构域

    C-Term

    序列

    IFDGTDACVT PVLTFEEVVH HDHNKERGSF ITSEEQDVSP RPAPLLLNTP

    产品特性

    This is a synthetic peptide designed for use in combination with anti-AMACR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

    背景

    This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

    Alias Symbols: CBAS4, RACE, RM, AMACRD

    Protein Size: 382

    分子量

    42 kDa

    基因ID

    23600

    NCBI登录号

    NM_014324, NP_055139

    UniProt

    Q9UHK6
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