Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (Middle Region) Peptide
ALS2
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN973149
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (Middle Region) Peptide (ABIN973149)
抗原
ALS2
(Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
-
-
蛋白结构域
- Middle Region
-
序列
- ALRGMSDLPP YGSGSSVQRQ EPPISRSAKY TFYKDPRLKD ATYDGRWLSG
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-ALS2 Antibody(ARP57487_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
纯化方法
- Purified
-
-
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
浓度
- 1 mg/mL
-
缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
-
背景
-
The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ALS2CR6, ALSJ, FLJ31851, IAHSP, KIAA1563, MGC87187, PLSJ
Protein Interaction Partner: YWHAB
Protein Size: 1657 -
分子量
- 184 kDa
-
基因ID
- 57679
-
NCBI登录号
- NM_020919, NP_065970
-
UniProt
- Q96Q42
抗原
-
You are here:
