Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (N-Term) Peptide
ALDH18A1
适用: 人
宿主: 合成
BP, WB
Quick Overview for Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (N-Term) Peptide (ABIN973099)
抗原
P5CS (ALDH18A1)
(Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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产品特性
- This is a synthetic peptide designed for use in combination with anti-ALDH18A1 antibody (Catalog #: ARP56216_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))
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背景
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This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases.This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.
Alias Symbols: GSAS, MGC117316, P5CS, PYCS, ARCL3A
Protein Interaction Partner: ZRANB1
Protein Size: 793 -
分子量
- 87 kDa
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基因ID
- 5832
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NCBI登录号
- NM_001017423, NP_001017423
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UniProt
- P54886
抗原
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