(1 reference)Quick Overview for Aminolevulinate, delta-, Synthase 1 (ALAS1) Peptide (ABIN973092)
抗原
ALAS1
(Aminolevulinate, delta-, Synthase 1 (ALAS1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-ALAS1 antibody (Catalog #: ARP54346_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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: "Renal Function Decline With Small Interfering RNA Silencing Aminolevulinic Acid Synthase 1 (ALAS1)." in: Kidney international reports, Vol. 6, Issue 7, pp. 1904-1911, (2021) (PubMed).
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: "Renal Function Decline With Small Interfering RNA Silencing Aminolevulinic Acid Synthase 1 (ALAS1)." in: Kidney international reports, Vol. 6, Issue 7, pp. 1904-1911, (2021) (PubMed).
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- ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))
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背景
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Delta-aminolevulinate synthase (ALAS, EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.
Alias Symbols: ALAS, ALAS3, ALASH, MIG4
Protein Interaction Partner: STAMBP
Protein Size: 640 -
分子量
- 70 kDa
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基因ID
- 211
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NCBI登录号
- NM_000688, NP_000679
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UniProt
- P13196
抗原
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