AKT1 Substrate 1 (Proline-Rich) (AKT1S1) Peptide
AKT1S1
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN973083
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for AKT1 Substrate 1 (Proline-Rich) (AKT1S1) Peptide (ABIN973083)
抗原
PRAS40 (AKT1S1)
(AKT1 Substrate 1 (Proline-Rich) (AKT1S1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-AKT1S1 antibody (Catalog #: ARP48061_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))
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背景
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AKT1S1 may play an important role in phosphatidylinositol 3-kinase (PI3K)-AKT1 survival signaling. It is the substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. Its role in survival signaling pathways may be modulated by oxidative stress. AKT1S1 may also play a role in nerve growth factor-mediated neuroprotection.AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM].
Alias Symbols: Lobe, MGC2865, PRAS40
Protein Interaction Partner: AKT1,AKT2,EIF6,MTOR,TCEA2,YWHAG,EIF6,TCEA2
Protein Size: 256 -
分子量
- 27 kDa
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基因ID
- 84335
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NCBI登录号
- NM_032375, NP_115751
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UniProt
- Q96B36
抗原
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