Amino-terminal Enhancer of Split (AES) (Middle Region) Peptide
AES
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all AES products
- AES (Amino-terminal Enhancer of Split (AES))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-AES antibody (Catalog #: ARP32323_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- AES (Amino-terminal Enhancer of Split (AES))
- 背景
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AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes.The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AES-1, AES-2, ESP1, GRG, GRG5, TLE5
Protein Interaction Partner: AES,RELA,SIX1,SIX2,SIX3,SIX6,PTRH2,AR,ATN1,CCL7,GABARAP,GFI1B,GTF2E1,HMGB1,MED31,MSX1,POU2F1,PRDM1,PTRH2,RELA,RPL18A,SH3GL3,SIX1,SIX2,SIX3,SIX6,SNCAIP,AES,AR,GTF2E1,HMGB1,HNF1A,HNRNPAB,MED31,PTRH2,RELA,RUNX1,SH3GL3,SIX3,SIX6,STYXL1,TLE1,TLE3
Protein Size: 264 - 分子量
- 29 kDa
- 基因ID
- 166
- NCBI登录号
- NM_198969, NP_945320
- UniProt
- Q14CJ1
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