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Adrenergic, beta-2-, Receptor, Surface (ADRB2) (Middle Region) Peptide

ADRB2 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN972964
发货至: 中国

Quick Overview for Adrenergic, beta-2-, Receptor, Surface (ADRB2) (Middle Region) Peptide (ABIN972964)

抗原

beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

宿主

资源

  • 10
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    Middle Region

    产品特性

    This is a synthetic peptide designed for use in combination with anti-ADRB2 antibody (Catalog #: AVARP00006_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

    背景

    This protein is beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: ADRB2R, ADRBR, B2AR, BAR, BETA2AR

    Protein Interaction Partner: EIF2B1,SLC9A3R1,SLC9A3R2,ADRB3,AKAP12,AKAP5,ARR3,ARRB1,CSK,EIF2B1,GNA11,GNA14,GNA15,GPRASP1,GRB2,GRK5,GRK6,HTR4,IL1B,INSR,KCNJ6,KCNJ9,NOS1,OPRD1,PRKCD,SLC9A3R1,SLC9A3R2,SRC,ADRB2,ADRBK1,AKAP12,Arrb2,EIF2B1,GRB2,GRK6,KCNJ3,KCNJ5,OPRD1,PPP3CA,SLC9A3R1,SLC9A3R2,SRC,UBC

    Protein Size: 413

    分子量

    46 kDa

    基因ID

    154

    NCBI登录号

    NM_000024, NP_000015

    UniProt

    P07550
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