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Adrenomedullin (ADM) (C-Term) Peptide

ADM 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN972946
发货至: 中国
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Quick Overview for Adrenomedullin (ADM) (C-Term) Peptide (ABIN972946)

抗原

Adrenomedullin (ADM)

宿主

资源

  • 3
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    C-Term

    序列

    VAPRSKISPQ GYGRRRRRSL PEAGPGRTLV SSKPQAHGAP APPSGSAPHF

    产品特性

    This is a synthetic peptide designed for use in combination with anti-ADM Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    Adrenomedullin (ADM)

    物质类

    Hormone

    背景

    Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.

    Alias Symbols: AM

    Protein Interaction Partner: ADM,CALCRL,CFH,EDN1,MME

    Protein Size: 185

    分子量

    20 kDa

    基因ID

    133

    NCBI登录号

    NM_001124, NP_001115

    UniProt

    P35318
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