alpha-2-Macroglobulin (A2M) (N-Term) Peptide
A2M
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all alpha 2 Macroglobulin (A2M) products
- alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- PVPGHVTVSI CRKYSDASDC HGEDSQAFCE KFSGQLNSHG CFYQQVKTKV
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-A2M Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
- 背景
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Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
Alias Symbols: CPAMD5, DKFZp779B086, FWP007, S863-7, A2MD
Protein Interaction Partner: ADAM19,ADAMTS1,AMBP,ANXA6,APOE,ATF7IP,B2M,C11orf58,CELA1,CTSB,CTSE,HSPA5,IL10,IL1B,KLK2,KLK3,LCAT,LEP,LRP1,LYZ,MMP2,MYOC,NGF,PAEP,PDGFA,PDGFB,SHBG,TGFBI,STAT3,ADAMTS1,AMBP,ANXA7,APOE,B2M,C11orf58,CDC42,CDK2AP2,CDKN1A,CPB2,GEM,GRB2,H2AFX,HMOX2,HSPA5,IL10,IL4,KLK13,KLK3,LCAT,LEP,LRP1,MMP2,NGF,NUDT21,PAEP,RAP1B,RPP14,SEPT8,SMN1,TGIF1,TK1,TNFRSF14,TSC22D1,TTR,UFD1L
Protein Size: 1474 - 分子量
- 161 kDa
- 基因ID
- 2
- NCBI登录号
- NM_000014, NP_000005
- UniProt
- P01023
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