This is a synthetic peptide designed for use in combination with anti-A2M Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
Alias Symbols: CPAMD5, DKFZp779B086, FWP007, S863-7, A2MD
Protein Interaction Partner: ADAM19,ADAMTS1,AMBP,ANXA6,APOE,ATF7IP,B2M,C11orf58,CELA1,CTSB,CTSE,HSPA5,IL10,IL1B,KLK2,KLK3,LCAT,LEP,LRP1,LYZ,MMP2,MYOC,NGF,PAEP,PDGFA,PDGFB,SHBG,TGFBI,STAT3,ADAMTS1,AMBP,ANXA7,APOE,B2M,C11orf58,CDC42,CDK2AP2,CDKN1A,CPB2,GEM,GRB2,H2AFX,HMOX2,HSPA5,IL10,IL4,KLK13,KLK3,LCAT,LEP,LRP1,MMP2,NGF,NUDT21,PAEP,RAP1B,RPP14,SEPT8,SMN1,TGIF1,TK1,TNFRSF14,TSC22D1,TTR,UFD1L