Estrogen Receptor 1 (ESR1) Peptide
ESR1
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
Quick Overview for Estrogen Receptor 1 (ESR1) Peptide (ABIN940517)
抗原
Estrogen Receptor alpha (ESR1)
(Estrogen Receptor 1 (ESR1))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- LLEMLDAHRL HAPTSRGGAS VEETDQSHLA TAGSTSSHSL QKYYITGEAE
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of ESR1 antibody,
Alternative Names: ESR1 control peptide, ESR1 antibody Blocking Peptide, Anti-ESR1 Blocking Peptide, estrogen receptor 1 Blocking Peptide, DKFZp686N23123 Blocking Peptide, ER Blocking Peptide, ESR Blocking Peptide, ESRA Blocking Peptide, Era Blocking Peptide, NR3A1 Blocking Peptide, ESR1, ESR-1, ESR 1, ESR-1 Blocking Peptide, ESR 1 Blocking Peptide -
纯化方法
- Antiserum
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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背景
- ESR1 is an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
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分子量
- 66 kDa
抗原
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