A synthetic peptide for use as a blocking control in assays to test for specificity of GLE1 antibody, Alternative Names: GLE1 control peptide, GLE1 antibody Blocking Peptide, Anti-GLE1 Blocking Peptide, Gle1 Rna Export Mediator Homolog Blocking Peptide, GLE1L Blocking Peptide, hGLE1 Blocking Peptide, GLE1, GLE-1, GLE 1, GLE-1 Blocking Peptide, GLE 1 Blocking Peptide
GLE1 is a predicted 75 kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes.