A synthetic peptide for use as a blocking control in assays to test for specificity of Lpcat2 antibody, Alternative Names: Lpcat2 control peptide, Lpcat2 antibody Blocking Peptide, Anti-Lpcat2 Blocking Peptide, lysophosphatidylcholine acyltransferase 2 Blocking Peptide, A330042H22 Blocking Peptide, Aytl1 Blocking Peptide, LPCAT2 Blocking Peptide, lpafat1 Blocking Peptide, Lpcat2, Lpcat-2, Lpcat 2, Lpcat-2 Blocking Peptide, Lpcat 2 Blocking Peptide
Lpcat2 possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. It is involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). It also converts lyso-PAF to 1-alkyl-phosphatidylcholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases.