A synthetic peptide for use as a blocking control in assays to test for specificity of SUV39 H2 antibody, Alternative Names: SUV39H2 control peptide, SUV39H2 antibody Blocking Peptide, Anti-SUV39H2 Blocking Peptide, Suppressor Of Variegation 3-9 Homolog 2 Blocking Peptide, FLJ23414 Blocking Peptide, KMT1B Blocking Peptide, SUV39H2, SUVH2-39, SUVH2 39, SUVH2-39 Blocking Peptide, SUVH2 39 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
SUV39H2
(Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
背景
SUV39H2 is a histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats.