Suppressor of Cytokine Signaling 7 (SOCS7) Peptide
SOCS7
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
Quick Overview for Suppressor of Cytokine Signaling 7 (SOCS7) Peptide (ABIN940239)
抗原
SOCS7
(Suppressor of Cytokine Signaling 7 (SOCS7))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
蛋白类型
- Synthetic
-
序列
- LDPKALPPGL ALERTWGPAA GLEAQLAALG LGQPAGPGVK TVGGGCCPCP
-
产品特性
-
A synthetic peptide for use as a blocking control in assays to test for specificity of SOCS7 antibody,
Alternative Names: SOCS7 control peptide, SOCS7 antibody Blocking Peptide, Anti-SOCS7 Blocking Peptide, Suppressor Of Cytokine Signaling 7 Blocking Peptide, NAP4 Blocking Peptide, SOCS7, SOCS-7, SOCS 7, SOCS-7 Blocking Peptide, SOCS 7 Blocking Peptide
-
-
-
-
应用备注
- Optimal conditions should be determined by the investigator
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
-
缓冲液
- PBS
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C long term.
-
-
- SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
-
背景
- SOCS7 regulates signaling cascades probably through protein ubiquitination and/or sequestration. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. SOCS7 may be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
-
分子量
- 64 kDa
抗原
-
You are here:
