Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) Peptide
RASSF1
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
Quick Overview for Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) Peptide (ABIN940157)
抗原
RASSF1
(Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- LAGPSDKALS FVLKENDSGE VNWDAFSMPE LHNFLRILQR EEEEHLRQIL
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of RASSF1 antibody,
Alternative Names: RASSF1 control peptide, RASSF1 antibody Blocking Peptide, Anti-RASSF1 Blocking Peptide, Ras association, RalGDS/AF-6 domain family member 1 Blocking Peptide, 123F2 Blocking Peptide, NORE2A Blocking Peptide, RASSF1A Blocking Peptide, RDA32 Blocking Peptide, REH3P21 Blocking Peptide, RASSF1, RASSF-1, RASSF 1, RASSF-1 Blocking Peptide, RASSF 1 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
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背景
- This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
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分子量
- 30 kDa
抗原
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