Apolipoprotein E (APOE) Peptide
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北京 101111
Quick Overview for Apolipoprotein E (APOE) Peptide (ABIN940102)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- KVLWAALLVT FLAGCQAKVE QAVETEPEPE LRQQTEWQSG QRWELALGRF
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of APOE antibody,
Alternative Names: ApoE control peptide, ApoE antibody Blocking Peptide, Anti-ApoE Blocking Peptide, Apolipoprotein E Blocking Peptide, AD2 Blocking Peptide, MGC1571 Blocking Peptide, apoprotein Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- APOE (Apolipoprotein E (APOE))
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背景
- Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
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分子量
- 34 kDa
抗原
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