A synthetic peptide for use as a blocking control in assays to test for specificity of POLG2 antibody, Alternative Names: POLG2 control peptide, POLG2 antibody Blocking Peptide, Anti-POLG2 Blocking Peptide, polymerase, DNA directed, gamma 2, accessory subunit Blocking Peptide, HP55 Blocking Peptide, MTPOLB Blocking Peptide, PEOA4 Blocking Peptide, POLB Blocking Peptide, POLG-BETA Blocking Peptide, POLGB Blocking Peptide, POLG2, POLG-2, POLG 2, POLG-2 Blocking Peptide, POLG 2 Blocking Peptide
This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.